Caffeine
The world's most-used stimulant. Most people already know their own limit.
Caffeine blocks adenosine, a molecule that builds up through the day and makes you feel drowsy, which is how it produces alertness and delays the feeling of fatigue. It has a half-life of roughly five hours in most adults, so an afternoon dose can still be affecting sleep well into the evening. European food safety guidance treats up to 400mg a day as a reasonable ceiling for healthy adults, roughly four cups of filter coffee, though individual sensitivity varies considerably and is shaped partly by genetics. It is commonly paired with L-theanine, which appears to soften the jittery edge of caffeine while alertness is largely retained.
How it pairs with other supplements
Works well with
EGCG inhibits catecholamine breakdown while caffeine stimulates release; combined effect on fat oxidation exceeds either alone (Hursel 2009).
Stack Almanac totals your caffeine across coffee, tea, pre-workouts, and standalone supplements, all logged in one place instead of estimated separately.
Track your Caffeine in Stack Almanac
Last reviewed: 2026-07-08. Reference values are adult-general RDAs. Individual needs may vary. This page is for informational purposes only and is not a substitute for professional medical advice.