VitaminsFat-soluble

Vitamin A

One of the few vitamins where more is genuinely riskier, especially in pregnancy.

Vitamin A supports vision, immune function, and skin health, and it comes in two very different dietary forms: preformed retinol from animal foods and supplements, and beta-carotene from orange and dark-green vegetables, which the body converts to retinol as needed. That conversion step is exactly why beta-carotene is the safer route to high intakes: retinol accumulates in the liver and is genuinely teratogenic at high doses, which is why UK guidance sets a lower precautionary ceiling on preformed retinol for women of childbearing age, and why pregnant women are advised against high-dose retinol supplements specifically.

Reference values

Daily reference values from official nutrition authorities. These are population reference figures, not personal recommendations.

GroupRDAUpper limitSource
General adult700 mcg1500 mcgUK SACN DRVs -- pregnancy: RNI +100 mcg/day in last trimester (combined 700 mcg RAE). NHS/SACN advise against high-dose preformed retinol in pregnancy; UL 1500 mcg/day from supplements. Beta-carotene does not carry teratogen risk.
Women, 19+600 mcg1500 mcgUK SACN DRVs (1991) -- women 600 mcg RAE/day; UL set conservatively at 1500 mcg/day preformed retinol for women of childbearing age due to teratogen risk (SACN / NHS advice)
Men, 19+700 mcg3000 mcgUK SACN DRVs (1991) -- men 700 mcg RAE/day; EFSA UL 3000 mcg RAE/day total vitamin A (2006). SACN advises preformed retinol supplements not exceed 1500 mcg/day (teratogen risk)

Forms and bioavailability

Not all forms are absorbed equally. The form on your supplement label affects how much your body can actually use.

FormAbsorptionWith foodTimingEvidence
Retinyl palmitate (preformed)TypicalWith foodMorningStrong
Retinol (preformed)TypicalWith foodMorningStrong
Beta-carotene (pro-vitamin A)LowerWith foodMorningLikely

How it pairs with other supplements

Works well with

Vitamins A and D share the RXR nuclear receptor heterodimerisation pathway and co-regulate gene expression. At normal supplement doses they are complementary. At high preformed retinol doses (>3000 mcg RAE/day) vitamin A may competitively impair vitamin D receptor signalling -- avoid very high retinol stacking with vitamin D.

ZincLikely

Zinc is required for synthesis and release of retinol-binding protein (RBP) from the liver, which transports vitamin A to target tissues. Zinc deficiency impairs vitamin A status independent of liver stores.

Stack Almanac tracks whether your vitamin A is coming from retinol or beta-carotene, and flags a high retinol total for extra caution if you're a woman of childbearing age.

Track your Vitamin A in Stack Almanac

Last reviewed: 2026-07-08. Reference values are adult-general RDAs from UK. Individual needs may vary. This page is for informational purposes only and is not a substitute for professional medical advice.