What is Stack Almanac?

Stack Almanac is a supplement tracking and analysis application. It organises a supplement routine, checks timing and pairings, records changes and outcomes, and provides a conversational advisor that cites sources.

How much does Stack Almanac cost?

Stack Almanac is free to use with supplement tracking, 5 advisor messages a day, an interaction checker, data export, and 10 scans a day up to 30 free scans in total. Pro costs £9.99/month and includes 30 standard and 5 advanced-analysis advisor messages a day, deeper insights, wearable data, weekly summaries, and 50 scans a day. Every new account starts with a 7-day Pro trial, no card required.

How is Stack Almanac different from other supplement trackers?

Stack Almanac keeps supplement names, forms, doses, timing, reasons, and routine changes together with reference information and a source-citing advisor. It can surface details worth reviewing and describe associations in recorded data. It does not prove cause, diagnose, or make personal safety decisions.

Comparison

Omega-3 EPA and DHA ratios

EPA and DHA are not interchangeable, which is why the ratio on the box differs. What it buys you is smaller than the label implies.

Fish oils vary their EPA to DHA split because the two fatty acids do measurably different things. A 2018 systematic review of head-to-head trials found both lower triglycerides, with DHA lowering them more; DHA raised HDL cholesterol and also raised LDL, while EPA did neither; and DHA improved vascular function, heart rate and blood pressure more than EPA. Both reduced platelet activity. Effects on inflammatory markers and blood sugar control came out inconclusive. Read that with its limits attached: six studies, 527 people, all using more than 2g a day of one fatty acid at 90% purity or better, which is several times what a standard capsule delivers. The ratio matters less than getting a sensible combined dose from a form you will keep taking. Plant omega-3 is not a shortcut: conversion of alpha-linolenic acid to EPA in adults is limited, and onward conversion to DHA is very low.

Stack Almanac totals your omega-3 across every product you log and records which form each one is, so a fish oil and an algae oil taken for different reasons read as one running intake rather than two separate habits.

What this is based on

1.The Differential Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Cardiometabolic Risk Factors: A Systematic ReviewInternational Journal of Molecular Sciences 2018;19(2):532DHA greater triglyceride lowering; DHA raises HDL and LDL, EPA does not; DHA better on vascular function, heart rate and blood pressure; 6 studies, 527 participants, >2 g/day at 90%+ purity; authors call for confirmation in larger trials
2.Effects of eicosapentaenoic acid versus docosahexaenoic acid on serum lipids: a systematic review and meta-analysisCurrent Atherosclerosis Reports 2011;13(6):474-83DHA raised LDL 4.63 mg/dL more than EPA in direct comparisons; both reduced triglycerides, DHA more; DHA raised HDL, EPA did not
3.Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adultsReproduction Nutrition Development 2005;45(5):581-97conversion of ALA to EPA is limited in men and onward conversion to DHA very low; raising ALA intake does not increase DHA
4.Seafood Long-Chain n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: A Science Advisory From the American Heart AssociationCirculation 2018;138(1):e35-e471 to 2 seafood meals per week; advice framed around seafood intake rather than a supplement EPA:DHA ratio

See also the full reference for omega 3.

Stack Almanac does this comparison against your own stack